COTA’s recent collaboration with University of Texas Southwestern Medical Center produced an analysis about Acute myeloid leukemia.
This study looked at the concordance of physician-assessed response in the COTA real-world database to derived response using the 2017 ELN criteria as the established standard for response assessment in clinical trials. They found that overall agreement between response categories was 65.1% with the highest agreement among CR (61.7%). In the subset of ELN eligible population the overall response was 80% for derived responders and 79% for physician-assessed responders.
